SB-612111 hydrochloride is a potent, novel orphan receptor for opioid receptors (ORL-1) antagonist with high affinity for hORL-1 and a Ki value of 0.33 nM. SB-612111 hydrochloride is able to act on mu-receptor (Ki: 57.6 nM), kappa SB-612111 hydrochloride effectively antagonized the nociceptive effects of Nociceptin in an acute pain model.
Molecular Weight:
454.86
Formula:
C24H30Cl3NO
Target:
Opioid Receptor|||Others
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