FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, demonstrating efficacy against FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM), and FLT3-ITD (IC50: 0.9 nM). It significantly inhibits FLT3 phosphorylation and effectively suppresses the proliferation of AML cells.
Molecular Weight:
455.94
CAS Number:
[2489446-47-9]
Formula:
C22H26ClN7O2
Target:
Others|||FLT
T62824
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