Tinlorafenib (PF-07284890) (compound 10) is an orally active, central nervous system (CNS)-permeable BRAF kinase inhibitor targeting BRAFV600E (IC50: 4.25 nM) and V600K (IC50: 2.7 nM). Tinlorafenib is applicable for studying BRAF-associated malignant and benign tumors of the CNS and extracranial malignancies.
Molecular Weight:
456.89
CAS Number:
[2573781-75-4]
Formula:
C19H19ClF2N4O3S
Target:
Raf|||ERK|||Others
T62841
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