GEM144 is a dual inhibitor of DNA polymerase alpha (POLA1) and HDAC 11. GEM144 induces p53 acetylation, activates p21, arrests the cell cycle in the G1/S phase, and induces apoptosis.
Molecular Weight:
461.55
Purity:
98.10%
CAS Number:
[2487526-28-1]
Formula:
C28H31NO5
Target:
Apoptosis|||HDAC|||DNA/RNA Synthesis|||p53
T62916
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