MIR002 is a potent, orally active dual inhibitor of DNA polymerase alpha (POLA1) and HDAC 11 with significant in vivo antitumor activity. p53 acetylation, p21 activation, cell cycle arrest in G1/S phase, and apoptosis induction.
Molecular Weight:
447.52
CAS Number:
[2217671-64-0]
Formula:
C27H29NO5
Target:
Apoptosis|||HDAC|||Others|||DNA/RNA Synthesis
T62917
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