KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C with an IC50 of 3.37 µM. It exhibits p-ERK inhibition with an IC50 of 9.25 µM in MIA PaCA-2 cells and greater than 33.3 µM in A549 cells. KRAS inhibitor-17 has potential applications in the study of pancreatic, colorectal, and lung cancers.
Molecular Weight:
466.36
CAS Number:
[2230873-65-9]
Formula:
C21H18Cl2FN3O2S
Target:
Kras|||Others|||Ras
T62981
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