IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. It inhibits cell IDO1 with an EC50 of 30 nM for HeLa cells and reduces the kyn/trp ratio by 51% in SK-OV-3 xenograft tumor tissue.
Molecular Weight:
470.34
Formula:
C20H16BrN5O2S
Target:
Others|||Indoleamine 2,3-Dioxygenase (IDO)|||IDO
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