ZMF-10 is a potent inhibitor of PAK1, and can act on PAK1 (IC50:174 nM), PAK2 (IC50:1.038 µM) and PAK3 (IC50:1.372 µM). ZMF-10 inhibited PAK1 activity and affected Pak1-regulated apoptosis, endoplasmic reticulum stress and migration in MDA-MB-231 cells. ZMF-10 can be used to study cancer.
Molecular Weight:
473.38
CAS Number:
[2415295-37-1]
Formula:
C19H17F6N7O
Target:
Apoptosis|||Others|||PAK
T63063
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