R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3alpha/beta, while inactive to other kinases. Phase 1.
Molecular Weight:
441.45
Purity:
90.00%
CAS Number:
[741713-40-6]
Formula:
C18H21F2N5O4S
Target:
Apoptosis|||GSK-3|||CDK|||PKA
T6312
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