APJ receptor agonist 5 (compound 3) is a potent and orally active apelin receptor (APJ) agonist (EC 50: 0.4 nM) with excellent pharmacokinetic profiles in rodent heart failure (HF) models and an acceptable safety profile in preclinical toxicology studies, improving cardiac function and useful for HF disease research.
Molecular Weight:
479.52
CAS Number:
[2135514-20-2]
Formula:
C26H29N3O6
Target:
Others|||Apelin receptor
T63153
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