KRAS inhibitor-13 (compound 5-6) is a potent inhibitor of KRAS G12C (IC50: 0.883 µM) and demonstrates a p-ERK inhibitory effect in MIA PaCA-2 and A549 cells with IC50 values of 5.9 µM and >100 µM respectively. KRAS inhibitor-13 has potential applications in pancreatic, colorectal, and lung cancer studies.
Molecular Weight:
479.95
CAS Number:
[2230873-96-6]
Formula:
C25H19ClFN3O2S
Target:
Others|||Ras|||Kras
T63164
* VAT and and shipping costs not included. Errors and price changes excepted
