The Antitrypanosomal agent 7 (compound 18c) is a potent anti-trypanosome agent and shows good ADME properties. The Antitrypanosomal agent 7 was more than two-fold more active against T. brucei (IC50: 0.71 µM) than Nifurtimox. Antitrypanosomal agent 7 has a strong interaction with DNA and can selectively bind to AT-rich DNA.
Molecular Weight:
407.51
CAS Number:
[2492436-38-9]
Formula:
C23H29N5O2
Target:
Others|||Parasite
T63167
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