OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kalpha, PI3Kbeta, PI3Kgamma or DNA-PK. Phase 1.
Molecular Weight:
406.44
Purity:
95%
CAS Number:
[936890-98-1]
Formula:
C21H22N6O3
Target:
Autophagy|||mTOR|||DNA-PK|||PI3K
T6319
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