HDAC1/2 and CDK2-IN-1 (compound 14d) are potent inhibitors of HDAC1, HDAC2, and CDK2 with IC50 values of 70.7, 23.1, and 0.80 µM, respectively. HDAC1/2 and CDK2-IN-1 can block the cell cycle and induce apoptosis, demonstrating good anti-tumor effects in vivo.
Molecular Weight:
483.95
CAS Number:
[2418559-01-8]
Formula:
C26H22ClN7O
Target:
Apoptosis|||Others|||HDAC|||CDK
T63209
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