BMS-566419 is an acridone-based inhibitor of inosine 5-monophosphate dehydrogenase, a rate-limiting enzyme in de novo guanosine nucleotide biosynthesis, and through suppression of lymphocyte proliferation it has demonstrated clinical utility as a research compound for investigating immunosuppression mechanisms and therapeutic strategies in transplant rejection.
Molecular Weight:
487.57
CAS Number:
[566161-24-8]
Formula:
C28H30FN5O2
Target:
Dehydrogenase
T63246
T63246
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