IRAK4-IN-15 is a selective and potent IRAK4 inhibitor (IC50: 0.002 µM) with good human PK prediction and low intrinsic clearance.IRAK4-IN-15 in combination with Acalabrutinib exhibited potent synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL.
Molecular Weight:
488.56
CAS Number:
[2667681-85-6]
Formula:
C25H29FN10
Target:
Others|||IRAK
T63262
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