HPK1-IN-3 is a selective, potent, ATP-competitive inhibitor of hematopoietic progenitor cell kinase 1 (HPK1, MAP4K1) (IC50: 0.25 nM). HPK1-IN-3 has IL-2 cellular potency and is able to act on human peripheral blood mononuclear cells (PBMC) with an EC50 value of 108 nM.
Molecular Weight:
490.45
Formula:
C23H22F4N6O2
Target:
Others|||MAPK
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