IRAK4-IN-19 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) with an IC50 of 4.3 nM. It inhibits LPS-induced IL23 production in THP and DC cells and suppresses arthritis development in arthritic model rats. IRAK4-IN-19 can be used to study arthritic diseases.
Molecular Weight:
492.52
Formula:
C25H26F2N8O
Target:
Others|||IRAK
* VAT and and shipping costs not included. Errors and price changes excepted
