20S Proteasome activator 1 is a 20S proteasome activator with IC50 values of 0.3 µM for trypsin-like sites, 0.7 µM for chymotrypsin-like sites, and 1.8 µM for caspase sites. It prevents the accumulation of pathogenic alpha-synuclein (A53T) mutants through translation in the cellular system, thereby reducing the probability of disease occurrence. 20S Proteasome activator 1 can be used to study neurodegenerative diseases.
Molecular Weight:
492.97
Purity:
99.68%
CAS Number:
[2761578-18-9]
Formula:
C27H19ClF2N2OS
Target:
Proteasome
T63321
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