HDAC-IN -45, a small molecule HDAC inhibitor, was able to form hydrogen bonds with Y303 residues and exhibited anticancer effects. HDAC-IN-45 significantly inhibited HDAC1, HDAC2 and HDAC3 subtypes with their IC50 values of 0.108, 0.585 and 0.563 µM, respectively.
Molecular Weight:
502.93
CAS Number:
[2421122-61-2]
Formula:
C25H20ClFN8O
Target:
Others|||HDAC
T63422
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