ERCC1-XPF-IN-1 is a potent, high-affinity inhibitor of ERCC1-XPF (IC50: 0.49 µM), that inhibits the removal of CPDs, reduces the toxicity of cyclophosphamide to colorectal cancer cells, enhances the cytotoxic effects of UV radiation, and impedes DNA repair.
Molecular Weight:
506.04
CAS Number:
[2411584-25-1]
Formula:
C28H32ClN5O2
Target:
DNA/RNA Synthesis|||Others
T63464
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