RET-IN-14 is a potent inhibitor of RET, capable of acting on RET (WT) (IC50 < 0.51 nM), RET (G810R) (IC50: 9.3 nM), RET (V804M) (IC50: 1.3 nM), BTK (C481S) (IC50: 9.2 nM) and BTK (C481S) (IC50 : 15 nM). RET-IN-14 exhibits potential for tumor studies.
Molecular Weight:
506.49
CAS Number:
[2755843-62-8]
Formula:
C24H23FN8O4
Target:
BTK|||Others|||c-RET
T63468
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