TCMDC-135051 hydrochloride is a potent, highly selective, low off-target toxicity inhibitor of the protein kinase PfCLK3. TCMDC-135051 hydrochloride blocks the trophozoite to lysosome transition, disrupts transcription and inhibits transmission to mosquito vectors, exhibiting an antiparasitic effect with an EC50 value of 320 nM.
Molecular Weight:
508.05
Formula:
C29H34ClN3O3
Target:
Others|||Parasite
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