P-gp inhibitor 5 is a potent P-glycoprotein (P-gp) inhibitor, reducing P-gp activity by a factor of 2.5 and 3.0 at 1.25 µM and 2.5 µM, respectively. It exhibits anti-proliferative effects on certain cancer cells and restores cellular sensitivity to Vincristine and Paclitaxel, reversing the multidrug resistant (MDR) phenotype of ABCB1/Flp-InTM-293 and KBvin.
Molecular Weight:
517.98
CAS Number:
[2451298-06-7]
Formula:
C28H20ClNO5S
Target:
Others|||P-gp
T63608
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