EGFR kinase inhibitor 1 is a potent inhibitor of EGFR that acts on WT (IC50: 37 nM), l885R/T790M (IC50: 1.7 nM), and L858R/T790M/C797S (IC50>300 nM). It is capable of blocking the cell cycle in G0/G1 phase, inducing apoptosis, and has an inhibitory effect on cell metastasis. Additionally, EGFR kinase inhibitor 1 exhibits anti-proliferative and anti-tumor effects.
Molecular Weight:
521.61
CAS Number:
[2413958-04-8]
Formula:
C30H31N7O2
Target:
Apoptosis|||EGFR|||Others
T63648
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