Vamotinib (PF-114) is an orally active and specific tyrosine kinase inhibitor with antiproliferative and antitumour activity.Vamotinib inhibits the phosphorylation of BCR/ABL and BCR/ABL-T315I, which promotes apoptosis. Vamotinib is used to study drug-resistant Philadelphia chromosome-positive (Ph+) leukaemia and Alzheimers disease.
Molecular Weight:
532.56
Purity:
99.64%
CAS Number:
[1416241-23-0]
Formula:
C29H27F3N6O
Target:
Bcr-Abl|||Tyrosine Kinases|||Apoptosis
T63746
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