AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.
Molecular Weight:
430.4
Purity:
99.85%
CAS Number:
[659730-32-2]
Formula:
C20H13F3N4O2S
Target:
TRP/TRPV Channel
T6379
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