AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38alpha, Tyk2, JNK2, Met, and Tie2. [Phase 1].
Molecular Weight:
503.58
Purity:
99.51%
CAS Number:
[945595-80-2]
Formula:
C28H21N7OS
Target:
p38 MAPK|||Aurora Kinase|||Tyrosine Kinases
T6380
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