Filgotinib (maleate) is a selective, orally active JAK1 inhibitor that effectively inhibits the activity of JAK1 (IC50: 10 nM), JAK2 (IC50: 28 nM), JAK3 (IC50: 810 nM) and TYK2 (IC50: 116 nM). maleate) can be used to study rheumatoid arthritis (RA) and Crohns disease.
Molecular Weight:
541.58
CAS Number:
[1802998-75-9]
Formula:
C25H27N5O7S
Target:
Others|||JAK|||HIV Protease
T63815
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