SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM). sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.
Molecular Weight:
550.57
CAS Number:
[2793405-20-4]
Formula:
C29H29F3N6O2
Target:
Others|||Kras|||Ras
T63887
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