(R)-(-)-Gossypol acetic acid (AT101 acetate), the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 µM, 0.48 µM, and 0.18 µM, respectively, it does not inhibit the BIR3 domain or BID. [Phase 2]
Molecular Weight:
578.61
Purity:
99.50%
CAS Number:
[866541-93-7]
Formula:
C30H30O8C2H4O2
Target:
Bcl-2 Family|||Autophagy
T6396
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