GSK3739936 is a potent inhibitor of HIV-1 allosteric integrase (IC50: 11.1 nM, EC50: 1.7 nM). GSK3739936 is also a weak inhibitor of CYP with an IC50 >24.3 µM. It has good pharmacokinetic properties with rapid absorption, low to moderate clearance and good oral bioavailability.
Molecular Weight:
562.71
CAS Number:
[1803444-21-4]
Formula:
C34H43FN2O4
Target:
Others|||HIV Protease
T63977
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