FAK-IN-2 is a potent, orally active adherens spot kinase (FAK) inhibitor (IC50: 35 nM) that exhibits antitumour effects. FAK-IN-2 covalently inhibits FAK autophosphorylation in a dose-dependent manner and also inhibits tumour cell formation and migration and induces apoptosis.
Molecular Weight:
563.05
Formula:
C28H31ClN8O3
Target:
FAK|||Apoptosis|||Others
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