AChE-IN-12 is a potent acetylcholinesterase (AChE) inhibitor that crosses the blood-brain barrier (BBB), targeting rat AChE (IC50: 0.41 µM) and electric eel AChE (IC50: 1.88 µM). It significantly inhibits Cu2+-induced aggregation of Abeta1-42, exhibits good neuroprotective effects, and may be used in Alzheimers disease studies.
