MAP855 is a potent, selective, orally active, ATP-competitive MEK1/2 kinase inhibitor with an IC50 value of 3 nM for MEK1 ERK2 cascade and a pERKEC50 value of 5 nM. MAP855 exhibits equal inhibition of wild-type and mutant MEK1/2.
Molecular Weight:
564.97
CAS Number:
[1660107-77-6]
Formula:
C28H23ClF2N6O3
Target:
MEK|||ERK|||Others
T64001
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