Pan-Trk-IN-3
Catalog Number:
TGM-T64070
| Article Name: |
Pan-Trk-IN-3 |
| Biozol Catalog Number: |
TGM-T64070 |
| Supplier Catalog Number: |
T64070 |
| Alternative Catalog Number: |
TGM-T64070-25MG,TGM-T64070-50MG,TGM-T64070-100MG |
| Manufacturer: |
TargetMol |
| Category: |
Biochemikalien |
| Pan-Trk-IN-3 is a potent, broad-spectrum inhibitor of Trk and its drug-resistant mutants, acting on TrkA (IC50: 2 nM), TrkB (IC50: 3 nM), TrkC (IC50: 2 nM), TrkAG595R (IC50: 21 nM), TrkAG667C (IC50: 26 nM), TrkAG667S (IC50: 5 nM), TrkAF589L (IC50: 7 nM) and TrkCG623R (IC50: 6 nM), TrkAG667S (IC50: 5 nM), TrkAF589L (IC50: 7 nM) and TrkCG623R (IC50: 6 nM). Pan-Trk-IN-3 induces apoptosis and has significant anti-tumour effects. |
| Molecular Weight: |
575.06 |
| Formula: |
C29H31ClN8O3 |
| Target: |
Others|||Trk receptor|||Apoptosis |
