c-Met-IN-12 is a selective, orally active type II c-Met kinase inhibitor (IC50: 10.6 nM). c-Met-IN-12 is a high inhibitor of AXL, Mer and TYRO3 kinases (>80% inhibition at 1 µM). c-Met-IN-12 can be used as a scaffold to further enhance kinase selectivity. c-Met-IN-12 exhibits anti-tumour activity.
Molecular Weight:
576.62
CAS Number:
[2426675-70-7]
Formula:
C34H29FN4O4
Target:
c-Met/HGFR|||Others
T64080
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