Anticancer agent 65 showed good results in tumour cell lines, especially A549 cells (IC50: 1.07 µM). anticancer agent 65 blocked the cell cycle of A549 cells in S phase, induced apoptosis, increased the expression of p53 and p21, and contributed to ROS generation and MMP collapse.
Molecular Weight:
589.89
CAS Number:
[2407861-48-5]
Formula:
C36H63NO5
Target:
Others|||MMP|||MDM-2/p53|||Apoptosis|||Bcl-2 Family|||Reactive Oxygen Species
T64179
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