JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor. JI6 exhibits IC50s of 40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits c-Kit and JAK3, with IC50s of 500 and 250 nM, respectively. JI6 has research value in acute myeloid leukemia.
Molecular Weight:
383.42
Purity:
99.09%
CAS Number:
[856436-16-3]
Formula:
C19H17N3O4S
Target:
JAK|||FLT|||c-Kit
T64370
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