TAME (Tosyl-Arginine Methyl Este), an inhibitor of the late-promoting complex (APC/C or APC), inhibits APC-dependent protein hydrolysis by competing for APC binding with the C-terminal isoleucine-arginine tail of the APC activator cytokinesis cycle 20 (Cdc20). TAME binds to and prevents APC binding by Cdc20 and Cdh20. TAME binds to APC and prevents its activation by Cdc20 and Cdh1.
Molecular Weight:
342.41
CAS Number:
[901-47-3]
Formula:
C14H22N4O4S
Target:
APC/C
T6693
T6693
* VAT and and shipping costs not included. Errors and price changes excepted