ML353 (VU0478006) is a selective activator of TREK-1 and TREK-2 and a selective ligand (Ki =18.2 nM) for the mGlu5 Silencing Allosteric Modulator (SAM). ML353 has potential as a solution to the intrinsic activity or pharmacological blockade of SAM in vivo.
Molecular Weight:
306.33
Purity:
99.98%
Formula:
C19H15FN2O
Target:
GluR|||Potassium Channel
T67917
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