Canfosfamide Hydrochloride is the hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation.
Molecular Weight:
823.93
CAS Number:
[439943-59-6]
Formula:
C26H41Cl5N5O10PS
Target:
DNA Alkylator/Crosslinker|||Others
T67975
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