Oxodipine, a dihydropyridine-type calcium antagonist, inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduced L-type Ca currents (I) with an IC of 0.24 µM, and against T-type Ca currents (I) with an IC of 0.41 µM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs.
Molecular Weight:
359.37
Purity:
99.64%
CAS Number:
[90729-41-2]
Formula:
C19H21NO6
Target:
Calcium Channel
T68123
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