Adriforant (PF-3893787,ZPL-3893797) is a competitive H4 (histamine receptor 4) antagonist that antagonizes histamine-induced phosphorylation of ERK, normalizes histamine-induced transcriptional changes in mast cells and reduces histamine-dependent Ca2+ fluxes in neurons, which alleviates itching and skin inflammation in mice
Molecular Weight:
262.35
Purity:
99.84%
CAS Number:
[943057-12-3]
Formula:
C13H22N6
Target:
Histamine Receptor
T68280
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