Annamycin is a semi-synthetic doxorubicin analogue annamycin with antineoplastic activity. Annamycin intercalates into DNA and inhibits topoisomerase II, resulting in the inhibition of DNA replication and repair and RNA and protein synthesis. This agent circumvents multidrug-resistance (MDR) transporters, including P-glycoprotein (P-gp).
Molecular Weight:
640.37
CAS Number:
[92689-49-1]
Formula:
C26H25IO11
Target:
Others|||Antibiotic
T68326
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