AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth.
Molecular Weight:
398.41
CAS Number:
[905585-60-6]
Formula:
C20H20F2N6O
Target:
Trk receptor|||Others
T68403
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