GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.
Molecular Weight:
389.45
Purity:
99.23%
CAS Number:
[1373422-53-7]
Formula:
C22H23N5O2
Target:
Histone Demethylase
T6847
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