Puupehenone is a natural heat shock protein 90 (Hsp90) inhibitor, potentiating the echinocandin drug caspofungin in caspofungin-resistant fungal pathogens, blocking the induction of caspofungin-responding genes required for the adaptation to cell wall stress through the cell wall integrity (CWI) pathway.
Molecular Weight:
328.45
CAS Number:
[73573-17-8]
Formula:
C21H28O3
Target:
Others
T68780
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