Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomyces cerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A is a lipopeptide that inhibits beta-glucan synthesis in yeasts. The inhibition is due to the selective blockage of glucan synthase. Aculeacin A, an amphophilic antibiotic, inhibits the biosynthesis of beta-glucan by selective blockage of beta(13) glucan synthase.
Molecular Weight:
1036.22
CAS Number:
[58814-86-1]
Formula:
C50H81N7O16
Target:
Others
T69051
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