Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor studied in acute myeloid leukemia and inhibits osteoclastogenesis and breast cancer-induced osteolysis via the P38/STAT3 signaling pathway.
Molecular Weight:
556.63
Purity:
0.9966
CAS Number:
[945614-12-0]
Formula:
C31H33FN6O3
Target:
Autophagy|||p38 MAPK|||Tie-2
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